A BIOCHEMICAL PROFILE ON PATIENTS WITH XANTHELASMA PALPEBRARUM: A CLINICAL STUDY

Abstract

Background: Xanthelasma palpebrarum refers to fat deposition that occurs on eyelids and inner canthi. It may be associated with certain systemic conditions. Aims: 1.To find the relationship between Xanthelasma palpebrarum and biochemical lipid profile. 2. To find the relationship between the parameters of age, sex, comorbid illness, with Xanthelasma palpebrarum. Methods: In this type of Case control study, 50 cases with Xanthelasma palpebrarum and 50 healthy individuals were selected. All cases and controls underwent clinical examination and fasting lipid profile study. Result: Total cholesterol levels were increased in 64% (32 cases) as compared to 19 controls (38%) with p=0.009, making it highly significant. LDL cholesterol levels were increased in 41 cases (82%) as compared to 30 controls (60%) making it statistically significant with a p value of 0.015. No significant relationship was observed with respect to other cholesterol parameters. Conclusion: This study shows that there is a significant elevation in total cholesterol and LDL cholesterol in Xanthelasma palpebrarum patients as compared to controls, thus making lipid profile compulsory for all patients with Xanthelasma.